the somatic nervous system regulates the activity of

The related neurotransmitter receptors are widely distributed in various intestinal cells. Innervation of the gastrointestinal tract includes extrinsic autonomic nerve system (ANS) and intrinsic enteric nervous system (ENS). It might be helpful to properly manipulate autonomic nervous system during treating different intestinal diseases. Function of autonomic nervous system on intestinal diseases was extensively reviewed.

How autonomic nervous system regulates intestinal cell proliferation was discussed. Presently, distribution and functional characteristics of autonomic nervous system in intestine were reviewed. Intestinal autonomic nerve system includes sympathetic and parasympathetic nervous systems, which regulate cellular proliferation and function in intestine under physiological and pathophysiological conditions. The neurotransmitters and counterpart receptors are widely distributed in the different intestinal cells. Intestine is innervated with extrinsic autonomic nerves and intrinsic enteric nerves. Intestine is composed of various types of cells including absorptive epithelial cells, goblet cells, endocrine cells, Paneth cells, immunological cells, and so on, which play digestion, absorption, neuroendocrine, immunological function. 3Jiangxi Provincial Key Laboratory of Interdisciplinary Science, Nanchang University, Nanchang, China.2Jiangxi Provincial Key Laboratory of Preventive Medicine, Nanchang University, Nanchang, China.1Medical College of Nanchang University, Nanchang, China.Hongyi Duan 1, Xueqin Cai 1, Yingying Luan 1, Shuo Yang 1,2, Juan Yang 1,2, Hui Dong 1,3, Huihong Zeng 1,3 and Lijian Shao 1,2,3*

The somatic nervous system regulates the activity of